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Targeting Autophagy in Cancer: Update on Clinical Trials and Novel Inhibitors

Eukaryotes use autophagy as a mechanism for maintaining cellular homeostasis by degrading and recycling organelles and proteins. This process assists in the proliferation and survival of advanced cancers. There is mounting preclinical evidence that targeting autophagy can enhance the efficacy of man...

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Detalles Bibliográficos
Publicado en:Int J Mol Sci
Main Authors: Chude, Cynthia I., Amaravadi, Ravi K.
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2017
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5486101/
https://ncbi.nlm.nih.gov/pubmed/28621712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18061279
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