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Transcriptional regulation of autophagy in RAS-driven cancers
RAS-driven cancers exhibit variable dependency on autophagy for survival; however, it is not fully understood how. In this issue of the JCI, Cheong and colleagues demonstrate that RAS-dependent elevation of casein kinase 1α (CK1α) negatively regulates autophagy at the level of autophagy gene transcr...
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| Pubblicato in: | J Clin Invest |
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| Autore principale: | |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Clinical Investigation
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4409024/ https://ncbi.nlm.nih.gov/pubmed/25798614 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI81504 |
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