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CRISPR/Cas9-Mediated Correction of the FANCD1 Gene in Primary Patient Cells
Fanconi anemia (FA) is an inherited condition characterized by impaired DNA repair, physical anomalies, bone marrow failure, and increased incidence of malignancy. Gene editing holds great potential to precisely correct the underlying genetic cause such that gene expression remains under the endogen...
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| Yayımlandı: | Int J Mol Sci |
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| Asıl Yazarlar: | , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
MDPI
2017
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5486091/ https://ncbi.nlm.nih.gov/pubmed/28613254 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18061269 |
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