Fanconi Anemia Gene Editing by the CRISPR/Cas9 System

Genome engineering with designer nucleases is a rapidly progressing field, and the ability to correct human gene mutations in situ is highly desirable. We employed fibroblasts derived from a patient with Fanconi anemia as a model to test the ability of the clustered regularly interspaced short palin...

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Dettagli Bibliografici
Pubblicato in:Hum Gene Ther
Autori principali: Osborn, Mark J., Gabriel, Richard, Webber, Beau R., DeFeo, Anthony P., McElroy, Amber N., Jarjour, Jordan, Starker, Colby G., Wagner, John E., Joung, J. Keith, Voytas, Daniel F., von Kalle, Christof, Schmidt, Manfred, Blazar, Bruce R., Tolar, Jakub
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2015
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4326027/
https://ncbi.nlm.nih.gov/pubmed/25545896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2014.111
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