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CRISPR/Cas9-Mediated Correction of the FANCD1 Gene in Primary Patient Cells
Fanconi anemia (FA) is an inherited condition characterized by impaired DNA repair, physical anomalies, bone marrow failure, and increased incidence of malignancy. Gene editing holds great potential to precisely correct the underlying genetic cause such that gene expression remains under the endogen...
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| 發表在: | Int J Mol Sci |
|---|---|
| Main Authors: | , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
MDPI
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5486091/ https://ncbi.nlm.nih.gov/pubmed/28613254 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18061269 |
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