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CRISPR/Cas9-Based Cellular Engineering for Targeted Gene Overexpression
Gene and cellular therapies hold tremendous promise as agents for treating genetic disorders. However, the effective delivery of genes, particularly large ones, and expression at therapeutic levels can be challenging in cells of clinical relevance. To address this engineering hurdle, we sought to em...
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| Pubblicato in: | Int J Mol Sci |
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| Autori principali: | , , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
MDPI
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5979553/ https://ncbi.nlm.nih.gov/pubmed/29565806 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19040946 |
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