Fanconi Anemia Gene Editing by the CRISPR/Cas9 System

Genome engineering with designer nucleases is a rapidly progressing field, and the ability to correct human gene mutations in situ is highly desirable. We employed fibroblasts derived from a patient with Fanconi anemia as a model to test the ability of the clustered regularly interspaced short palin...

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Publicat a:Hum Gene Ther
Autors principals: Osborn, Mark J., Gabriel, Richard, Webber, Beau R., DeFeo, Anthony P., McElroy, Amber N., Jarjour, Jordan, Starker, Colby G., Wagner, John E., Joung, J. Keith, Voytas, Daniel F., von Kalle, Christof, Schmidt, Manfred, Blazar, Bruce R., Tolar, Jakub
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2015
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4326027/
https://ncbi.nlm.nih.gov/pubmed/25545896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2014.111
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