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Synergistic down-regulation of receptor tyrosine kinases by combinations of mAbs: Implications for cancer immunotherapy

mAbs to receptor tyrosine kinases such as EGF receptor/ErbB-1 and HER2/ErbB-2 inhibit the tumorigenic growth of certain cancer cells, but although recombinant versions of such Abs are already used in oncology wards, the mechanism underlying immunotherapy remains unknown. We report that anti-EGF rece...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Friedman, Lilach M., Rinon, Ariel, Schechter, Bilha, Lyass, Ljuba, Lavi, Sara, Bacus, Sarah S., Sela, Michael, Yarden, Yosef
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: National Academy of Sciences 2005
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC548578/
https://ncbi.nlm.nih.gov/pubmed/15684082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409610102
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