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Synergistic potentiation of the anti-metastatic effect of anti EGFR mAb by its combination with immunotherapies targeting the ganglioside NGcGM3

Several Anti-EGFR mAbs are register for the treatment of human cancer. However, their impact on patients overall survival has been limited by tumor resistance. N-Glycolyl variant of GM3 ganglioside (NGcGM3) is specifically expressed in some human tumors, and it has been associated with a poor progno...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Palomo, Addys González, Medinilla, Armando López, Segatori, Valeria, Barroso, María del Carmen, Blanco, Rances, Gabri, Mariano R., Pérez, Adriana Carr, Monzón, Kalet León
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5963610/
https://ncbi.nlm.nih.gov/pubmed/29844873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25290
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