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Model‐based investigation of intracellular processes determining antibody Fc‐glycosylation under mild hypothermia
Despite the positive effects of mild hypothermic conditions on monoclonal antibody (mAb) productivity (q (mAb)) during mammalian cell culture, the impact of reduced culture temperature on mAb Fc‐glycosylation and the mechanism behind changes in the glycan composition are not fully established. The l...
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| Publicat a: | Biotechnol Bioeng |
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| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
John Wiley and Sons Inc.
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5485029/ https://ncbi.nlm.nih.gov/pubmed/27869292 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.26225 |
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