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Towards Controlling the Glycoform: A Model Framework Linking Extracellular Metabolites to Antibody Glycosylation

Glycoproteins represent the largest group of the growing number of biologically-derived medicines. The associated glycan structures and their distribution are known to have a large impact on pharmacokinetics. A modelling framework was developed to provide a link from the extracellular environment an...

詳細記述

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書誌詳細
主要な著者: Jedrzejewski, Philip M., del Val, Ioscani Jimenez, Constantinou, Antony, Dell, Anne, Haslam, Stuart M., Polizzi, Karen M., Kontoravdi, Cleo
フォーマット: Artigo
言語:Inglês
出版事項: Molecular Diversity Preservation International (MDPI) 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3975410/
https://ncbi.nlm.nih.gov/pubmed/24637934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms15034492
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