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A theoretical estimate for nucleotide sugar demand towards Chinese Hamster Ovary cellular glycosylation
Glycosylation greatly influences the safety and efficacy of many of the highest-selling recombinant therapeutic proteins (rTPs). In order to define optimal cell culture feeding strategies that control rTP glycosylation, it is necessary to know how nucleotide sugars (NSs) are consumed towards host ce...
Guardat en:
| Publicat a: | Sci Rep |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4921913/ https://ncbi.nlm.nih.gov/pubmed/27345611 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28547 |
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