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In Situ Monitoring of Intracellular Glucose and Glutamine in CHO Cell Culture

The development of processes to produce biopharmaceuticals industrially is still largely empirical and relies on optimizing both medium formulation and cell line in a product-specific manner. Current small-scale (well plate-based) process development methods cannot provide sufficient sample volume f...

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Bibliografiska uppgifter
Huvudupphovsmän: Behjousiar, Alireza, Kontoravdi, Cleo, Polizzi, Karen M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2012
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3317985/
https://ncbi.nlm.nih.gov/pubmed/22509313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034512
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