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In Situ Monitoring of Intracellular Glucose and Glutamine in CHO Cell Culture
The development of processes to produce biopharmaceuticals industrially is still largely empirical and relies on optimizing both medium formulation and cell line in a product-specific manner. Current small-scale (well plate-based) process development methods cannot provide sufficient sample volume f...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3317985/ https://ncbi.nlm.nih.gov/pubmed/22509313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034512 |
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