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Exploring cellular behavior under transient gene expression and its impact on mAb productivity and Fc‐glycosylation

Transient gene expression (TGE) is a methodology employed in bioprocessing for the fast provision of recombinant protein material. Mild hypothermia is often introduced to overcome the low yield typically achieved with TGE and improve specific protein productivity. It is therefore of interest to exam...

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Dades bibliogràfiques
Publicat a:Biotechnol Bioeng
Autors principals: Sou, Si N., Lee, Ken, Nayyar, Kalpana, Polizzi, Karen M., Sellick, Christopher, Kontoravdi, Cleo
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5765507/
https://ncbi.nlm.nih.gov/pubmed/28921534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.26456
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