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Exploring cellular behavior under transient gene expression and its impact on mAb productivity and Fc‐glycosylation

Transient gene expression (TGE) is a methodology employed in bioprocessing for the fast provision of recombinant protein material. Mild hypothermia is often introduced to overcome the low yield typically achieved with TGE and improve specific protein productivity. It is therefore of interest to exam...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biotechnol Bioeng
Prif Awduron: Sou, Si N., Lee, Ken, Nayyar, Kalpana, Polizzi, Karen M., Sellick, Christopher, Kontoravdi, Cleo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5765507/
https://ncbi.nlm.nih.gov/pubmed/28921534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.26456
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