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Exploring cellular behavior under transient gene expression and its impact on mAb productivity and Fc‐glycosylation

Transient gene expression (TGE) is a methodology employed in bioprocessing for the fast provision of recombinant protein material. Mild hypothermia is often introduced to overcome the low yield typically achieved with TGE and improve specific protein productivity. It is therefore of interest to exam...

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Detalhes bibliográficos
Publicado no:Biotechnol Bioeng
Main Authors: Sou, Si N., Lee, Ken, Nayyar, Kalpana, Polizzi, Karen M., Sellick, Christopher, Kontoravdi, Cleo
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5765507/
https://ncbi.nlm.nih.gov/pubmed/28921534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.26456
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