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Development of Radiolabeled Ligands Targeting the Glutamate Binding Site of the N-Methyl-d-aspartate Receptor as Potential Imaging Agents for Brain

Abnormal activity of various N-methyl-d-aspartate receptor (NMDAR) subtypes has been implicated in a wide variety of neurological disorders such as Alzheimer's disease, schizophrenia, and epilepsy. Imaging agents for PET and SPECT that target NMDARs in a subtype-selective fashion may enable bet...

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Publicado en:J Med Chem
Main Authors: Tamborini, Lucia, Chen, Ying, Foss, Catherine A., Pinto, Andrea, Horti, Andrew G., Traynelis, Stephen F., De Micheli, Carlo, Mease, Ronnie C., Hansen, Kasper B., Conti, Paola, Pomper, Martin G.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5484777/
https://ncbi.nlm.nih.gov/pubmed/28002957
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