Structure-based discovery of antagonists for GluN3-containing N-methyl-D-aspartate receptors

NMDA receptors are ligand-gated ion channels that assemble into tetrameric receptor complexes composed of glycine-binding GluN1 and GluN3 subunits (GluN3A-B) and glutamate-binding GluN2 subunits (GluN2A-D). NMDA receptors can assemble as GluN1/N2 receptors and as GluN3-containing NMDA receptors, whi...

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Hlavní autoři: Kvist, Trine, Greenwood, Jeremy R., Hansen, Kasper B., Traynelis, Stephen F., Bräuner-Osborne, Hans
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3865070/
https://ncbi.nlm.nih.gov/pubmed/23973313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2013.08.003
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