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Identification of AICP as a GluN2C-Selective N-Methyl-d-Aspartate Receptor Superagonist at the GluN1 Glycine Site

N-methyl-d-aspartate (NMDA)-type ionotropic glutamate receptors mediate excitatory neurotransmission in the central nervous system and are critically involved in brain function. NMDA receptors are also implicated in psychiatric and neurological disorders and have received considerable attention as t...

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Publicado en:Mol Pharmacol
Autores principales: Jessen, Maja, Frederiksen, Kristen, Yi, Feng, Clausen, Rasmus P., Hansen, Kasper B., Bräuner-Osborne, Hans, Kilburn, Paul, Damholt, Anders
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5508192/
https://ncbi.nlm.nih.gov/pubmed/28588066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.117.108944
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