Species-Specific Variation in the B30.2(SPRY) Domain of TRIM5α Determines the Potency of Human Immunodeficiency Virus Restriction

Retroviruses encounter dominant postentry restrictions in cells of particular species. Human immunodeficiency virus type 1 (HIV-1) is blocked in the cells of Old World monkeys by TRIM5α, a tripartite motif (TRIM) protein composed of RING, B-box 2, coiled-coil, and B30.2(SPRY) domains. Rhesus monkey...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Stremlau, Matthew, Perron, Michel, Welikala, Sohanya, Sodroski, Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2005
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC548447/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15709033/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.79.5.3139-3145.2005
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