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Functional Interplay Between the B-box 2 and the B30.2(SPRY) Domains of TRIM5α

The retroviral restriction factors, TRIM5α and TRIMCyp, consist of RING and B-box 2 domains separated by a coiled coil from carboxy-terminal domains. These carboxy-terminal domains (the B30.2(SPRY) domain in TRIM5α and the cyclophilin A domain in TRIMCyp) recognize the retroviral capsid. Here we sho...

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Detalhes bibliográficos
Main Authors: Li, Xing, Song, Byeongwoon, Xiang, Shi-Hua, Sodroski, Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2040257/
https://ncbi.nlm.nih.gov/pubmed/17543365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2007.04.022
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