The B30.2(SPRY) Domain of the Retroviral Restriction Factor TRIM5α Exhibits Lineage-Specific Length and Sequence Variation in Primates

Tripartite motif (TRIM) proteins are composed of RING, B-box 2, and coiled coil domains. Some TRIM proteins, such as TRIM5α, also possess a carboxy-terminal B30.2(SPRY) domain and localize to cytoplasmic bodies. TRIM5α has recently been shown to mediate innate intracellular resistance to retroviruse...

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Main Authors: Song, Byeongwoon, Gold, Bert, O'hUigin, Colm, Javanbakht, Hassan, Li, Xing, Stremlau, Matthew, Winkler, Cheryl, Dean, Michael, Sodroski, Joseph
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2005
נושאים:
Pathogenesis and Immunity
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1091705/
https://ncbi.nlm.nih.gov/pubmed/15857996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.10.6111-6121.2005
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