Species-Specific Variation in the B30.2(SPRY) Domain of TRIM5α Determines the Potency of Human Immunodeficiency Virus Restriction

Retroviruses encounter dominant postentry restrictions in cells of particular species. Human immunodeficiency virus type 1 (HIV-1) is blocked in the cells of Old World monkeys by TRIM5α, a tripartite motif (TRIM) protein composed of RING, B-box 2, coiled-coil, and B30.2(SPRY) domains. Rhesus monkey...

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Bibliografiske detaljer

Udgivet i:	J Virol
Principais autores:	Stremlau, Matthew, Perron, Michel, Welikala, Sohanya, Sodroski, Joseph
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 2005
Fag:	Virus-Cell Interactions
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC548447/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15709033/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.79.5.3139-3145.2005
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