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HDAC inhibitor-induced mitotic arrest is mediated by Eg5/KIF11 acetylation
Histone deacetylase 1 (HDAC1) is an epigenetic enzyme that regulates key cellular processes, such as cell proliferation, apoptosis, and cell survival, by deacetylating histone substrates. Aberrant expression of HDAC1 is implicated in multiple diseases, including cancer. As a consequence, HDAC inhibi...
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| Published in: | Cell Chem Biol |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5484148/ https://ncbi.nlm.nih.gov/pubmed/28392145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2017.03.008 |
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