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HDAC inhibitor-induced mitotic arrest is mediated by Eg5/KIF11 acetylation
Histone deacetylase 1 (HDAC1) is an epigenetic enzyme that regulates key cellular processes, such as cell proliferation, apoptosis, and cell survival, by deacetylating histone substrates. Aberrant expression of HDAC1 is implicated in multiple diseases, including cancer. As a consequence, HDAC inhibi...
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| 出版年: | Cell Chem Biol |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5484148/ https://ncbi.nlm.nih.gov/pubmed/28392145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2017.03.008 |
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