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HDAC1 Substrate Profiling using Proteomics-Based Substrate Trapping
Histone Deacetylase (HDAC) proteins are overexpressed in multiple diseases, including cancer, and have emerged as anticancer drug targets. HDAC proteins regulate cellular processes, such as cell cycle, apoptosis, and cell proliferation, by deacetylating histone and non-histone substrates. Although a...
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| Publicado no: | ACS Chem Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6563814/ https://ncbi.nlm.nih.gov/pubmed/30421914 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.8b00737 |
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