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HDAC1 Substrate Profiling using Proteomics-Based Substrate Trapping
Histone Deacetylase (HDAC) proteins are overexpressed in multiple diseases, including cancer, and have emerged as anticancer drug targets. HDAC proteins regulate cellular processes, such as cell cycle, apoptosis, and cell proliferation, by deacetylating histone and non-histone substrates. Although a...
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| Publicado en: | ACS Chem Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6563814/ https://ncbi.nlm.nih.gov/pubmed/30421914 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.8b00737 |
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