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Optimal substrate trapping mutants to discover substrates of HDAC1
Abstract Histone deacetylase 1 (HDAC1) regulates transcription by deacetylating histones. In addition to histones, several non-histone proteins are HDAC1 substrates, which verified a role for HDAC1 beyond epigenetics. Unfortunately, identification of nonhistone substrates has been largely serendipit...
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| Publicado no: | Chembiochem |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6858619/ https://ncbi.nlm.nih.gov/pubmed/30701667 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201800797 |
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