A Study of 11-[(3)H]-Tetrodotoxin Absorption, Distribution, Metabolism and Excretion (ADME) in Adult Sprague-Dawley Rats

Tetrodotoxin (TTX) is a powerful sodium channel blocker that in low doses can safely relieve severe pain. Studying the absorption, distribution, metabolism and excretion (ADME) of TTX is challenging given the extremely low lethal dose. We conducted radiolabeled ADME studies in Sprague-Dawley rats. A...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Mar Drugs
Autori principali: Hong, Bihong, Chen, Hui, Han, Jiacai, Xie, Quanling, He, Jianlin, Bai, Kaikai, Dong, Yanming, Yi, Ruizao
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2017
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5484109/
https://ncbi.nlm.nih.gov/pubmed/28574462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md15060159
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi