Study on the pharmacokinetics, tissue distribution and excretion of laurolitsine from Litsea glutinosa in Sprague-Dawley rats

CONTEXT: Laurolitsine is an aporphine alkaloid and exhibits potent antihyperglycemic and antihyperlipidemic effects in ob/ob mice. OBJECTIVE: To investigate the pharmacokinetics, tissue distribution and excretion of laurolitsine. MATERIALS AND METHODS: A LC-MS/MS method was established and validated...

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Enregistré dans:
Détails bibliographiques
Publié dans:Pharm Biol
Auteurs principaux: Tan, Yin-Feng, Wang, Rui-Qi, Wang, Wen-Ting, Wu, Ying, Ma, Ning, Lu, Wei-Ying, Zhang, Yong, Zhang, Xiao-Po
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2021
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8259838/
https://ncbi.nlm.nih.gov/pubmed/34219593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/13880209.2021.1944221
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