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Pore formation by dimeric Bak and Bax: an unusual pore?

Apoptotic cell death via the mitochondrial pathway occurs in all vertebrate cells and requires the formation of pores in the mitochondrial outer membrane. Two Bcl-2 protein family members, Bak and Bax, form these pores during apoptosis, and how they do so has been investigated for the last two decad...

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Bibliografiske detaljer
Udgivet i:Philos Trans R Soc Lond B Biol Sci
Main Authors: Uren, Rachel T., Iyer, Sweta, Kluck, Ruth M.
Format: Artigo
Sprog:Inglês
Udgivet: The Royal Society 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5483520/
https://ncbi.nlm.nih.gov/pubmed/28630157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2016.0218
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