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Synergistic Contribution of Tiglate and Cinnamate to Cytotoxicity of Ipomoeassin F
An efficient synthetic route for ipomoeassin F and its tiglate-modified analogues was developed. The route features late-stage conformation-controlled highly regioselective esterification of the glucose diol in the disaccharide core. The results from the NCI-60 cell line screens of ipomoeassin F wer...
Gardado en:
| Publicado en: | J Org Chem |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5483335/ https://ncbi.nlm.nih.gov/pubmed/28394135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.7b00409 |
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