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Design, Synthesis and Biological Evaluation of Fucose-Truncated Monosaccharide Analogues of Ipomoeassin F
Ipomoeassin F is a plant-derived macrocyclic glycolipid with single-digit nanomolar IC(50) values against cancer cell growth. In previous structure–activity relationship studies, we have demonstrated that certain modifications around the fucoside moiety did not cause significant cytotoxicity loss. T...
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| Vydáno v: | Bioorg Med Chem Lett |
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| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5502735/ https://ncbi.nlm.nih.gov/pubmed/28465102 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2017.04.065 |
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