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The C. elegans VAPB homolog VPR-1 is a permissive signal for gonad development

VAMP/synaptobrevin-associated proteins (VAPs) contain an N-terminal major sperm protein domain (MSPd) that is associated with amyotrophic lateral sclerosis. VAPs have an intracellular housekeeping function, as well as an extracellular signaling function mediated by the secreted MSPd. Here we show th...

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Detalles Bibliográficos
Publicado en:Development
Main Authors: Cottee, Pauline A., Cole, Tim, Schultz, Jessica, Hoang, Hieu D., Vibbert, Jack, Han, Sung Min, Miller, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado: The Company of Biologists Ltd 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5482997/
https://ncbi.nlm.nih.gov/pubmed/28634273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.152207
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