The secreted MSP domain of C. elegans VAPB homolog VPR-1 patterns the adult striated muscle mitochondrial reticulum via SMN-1

The major sperm protein domain (MSPd) has an extracellular signaling function implicated in amyotrophic lateral sclerosis. Secreted MSPds derived from the C. elegans VAPB homolog VPR-1 promote mitochondrial localization to actin-rich I-bands in body wall muscle. Here we show that the nervous system...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Schultz, Jessica, Lee, Se-Jin, Cole, Tim, Hoang, Hieu D., Vibbert, Jack, Cottee, Pauline A., Miller, Michael A., Han, Sung Min
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2017
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5482996/
https://ncbi.nlm.nih.gov/pubmed/28634272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.152025
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