VAPB/ALS8 MSP Ligands Regulate Striated Muscle Energy Metabolism Critical for Adult Survival in Caenorhabditis elegans

Mutations in VAPB/ALS8 are associated with amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy (SMA), two motor neuron diseases that often include alterations in energy metabolism. We have shown that C. elegans and Drosophila neurons secrete a cleavage product of VAPB, the N-terminal maj...

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Detaylı Bibliyografya
Asıl Yazarlar: Han, Sung Min, El Oussini, Hajer, Scekic-Zahirovic, Jelena, Vibbert, Jack, Cottee, Pauline, Prasain, Jeevan K., Bellen, Hugo J., Dupuis, Luc, Miller, Michael A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2013
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3764199/
https://ncbi.nlm.nih.gov/pubmed/24039594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003738
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