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The C. elegans VAPB homolog VPR-1 is a permissive signal for gonad development

VAMP/synaptobrevin-associated proteins (VAPs) contain an N-terminal major sperm protein domain (MSPd) that is associated with amyotrophic lateral sclerosis. VAPs have an intracellular housekeeping function, as well as an extracellular signaling function mediated by the secreted MSPd. Here we show th...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Cottee, Pauline A., Cole, Tim, Schultz, Jessica, Hoang, Hieu D., Vibbert, Jack, Han, Sung Min, Miller, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5482997/
https://ncbi.nlm.nih.gov/pubmed/28634273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.152207
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