Stability and function of regulatory T cells expressing the transcription factor T-bet

Adaptive immune responses are tailored to different types of pathogens through differentiation of naïve CD4 T cells into functionally distinct subsets of effector T cells (T(H)1, T(H)2, and T(H)17) defined by expression of key transcription factors (TFs)(1). Regulatory T (Treg) cells comprise a dist...

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Pubblicato in:Nature
Autori principali: Levine, Andrew G., Medoza, Alejandra, Hemmers, Saskia, Moltedo, Bruno, Niec, Rachel E., Schizas, Michail, Hoyos, Beatrice E., Putintseva, Ekaterina V., Chaudhry, Ashutosh, Dikiy, Stanislav, Fujisawa, Sho, Chudakov, Dmitriy M., Treuting, Piper M., Rudensky, Alexander Y.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5482236/
https://ncbi.nlm.nih.gov/pubmed/28607488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature22360
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