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Stability and function of regulatory T cells expressing the transcription factor T-bet

Adaptive immune responses are tailored to different types of pathogens through differentiation of naïve CD4 T cells into functionally distinct subsets of effector T cells (T(H)1, T(H)2, and T(H)17) defined by expression of key transcription factors (TFs)(1). Regulatory T (Treg) cells comprise a dist...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Levine, Andrew G., Medoza, Alejandra, Hemmers, Saskia, Moltedo, Bruno, Niec, Rachel E., Schizas, Michail, Hoyos, Beatrice E., Putintseva, Ekaterina V., Chaudhry, Ashutosh, Dikiy, Stanislav, Fujisawa, Sho, Chudakov, Dmitriy M., Treuting, Piper M., Rudensky, Alexander Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5482236/
https://ncbi.nlm.nih.gov/pubmed/28607488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature22360
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