Stability and function of regulatory T cells expressing the transcription factor T-bet

Adaptive immune responses are tailored to different types of pathogens through differentiation of naïve CD4 T cells into functionally distinct subsets of effector T cells (T(H)1, T(H)2, and T(H)17) defined by expression of key transcription factors (TFs)(1). Regulatory T (Treg) cells comprise a dist...

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Publié dans:Nature
Auteurs principaux: Levine, Andrew G., Medoza, Alejandra, Hemmers, Saskia, Moltedo, Bruno, Niec, Rachel E., Schizas, Michail, Hoyos, Beatrice E., Putintseva, Ekaterina V., Chaudhry, Ashutosh, Dikiy, Stanislav, Fujisawa, Sho, Chudakov, Dmitriy M., Treuting, Piper M., Rudensky, Alexander Y.
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5482236/
https://ncbi.nlm.nih.gov/pubmed/28607488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature22360
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