Suppression of lethal autoimmunity by regulatory T cells with a single TCR specificity

The regulatory T cell (T reg cell) T cell receptor (TCR) repertoire is highly diverse and skewed toward recognition of self-antigens. TCR expression by T reg cells is continuously required for maintenance of immune tolerance and for a major part of their characteristic gene expression signature; how...

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Veröffentlicht in:J Exp Med
Hauptverfasser: Levine, Andrew G., Hemmers, Saskia, Baptista, Antonio P., Schizas, Michail, Faire, Mehlika B., Moltedo, Bruno, Konopacki, Catherine, Schmidt-Supprian, Marc, Germain, Ronald N., Treuting, Piper M., Rudensky, Alexander Y.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2017
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Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5339675/
https://ncbi.nlm.nih.gov/pubmed/28130403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20161318
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