Lkb1 maintains T(reg) cell lineage identity

Regulatory T (T(reg)) cells are a distinct T-cell lineage characterized by sustained Foxp3 expression and potent suppressor function, but the upstream dominant factors that preserve T(reg) lineage-specific features are mostly unknown. Here, we show that Lkb1 maintains T(reg) cell lineage identity by...

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Pubblicato in:Nat Commun
Autori principali: Wu, Di, Luo, Yuechen, Guo, Wei, Niu, Qing, Xue, Ting, Yang, Fei, Sun, Xiaolei, Chen, Song, Liu, Yuanyuan, Liu, Jingru, Sun, Zhina, Zhao, Chunxiao, Huang, Huifang, Liao, Fang, Han, Zhongchao, Zhou, Dongming, Yang, Yongguang, Xu, Guogang, Cheng, Tao, Feng, Xiaoming
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5481770/
https://ncbi.nlm.nih.gov/pubmed/28621313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15876
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