Single-cell transcriptomic analysis reveals disparate effector differentiation pathways in human T(reg) compartment

Human FOXP3(+) regulatory T (T(reg)) cells are central to immune tolerance. However, their heterogeneity and differentiation remain incompletely understood. Here we use single-cell RNA and T cell receptor sequencing to resolve T(reg) cells from healthy individuals and patients with or without acute...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Luo, Yuechen, Xu, Changlu, Wang, Bing, Niu, Qing, Su, Xiuhua, Bai, Yingnan, Zhu, Shuxian, Zhao, Chunxiao, Sun, Yunyan, Wang, Jiali, Liu, Maolan, Sun, Xiaolei, Song, Ge, Cui, Haidong, Chen, Xiaoli, Huang, Huifang, Wang, Haikun, Han, Mingzhe, Jiang, Erlie, Shi, Lihong, Feng, Xiaoming
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8222404/
https://ncbi.nlm.nih.gov/pubmed/34162888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-24213-6
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