Control of T(reg) cell homeostasis and immune equilibrium by Lkb1 in dendritic cells

To balance immunity and tolerance, the endogenous pool of Foxp3(+) regulatory T (T(reg)) cells is tightly controlled, but the underlying mechanisms of this control remain poorly understood. Here we show that the number of T(reg) cells is negatively regulated by the kinase Lkb1 in dendritic cells (DC...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Nat Commun
Hlavní autoři: Chen, Song, Fang, Lijun, Guo, Wei, Zhou, Yushan, Yu, Gang, Li, Wenwen, Dong, Kui, Liu, Jingru, Luo, Yuechen, Wang, Bing, Li, Zhonglong, Zhao, Chunxiao, Sun, Zhina, Shen, Yue, Leng, Qibing, Zhou, Dongming, Han, Zhongchao, Huang, Huifang, Ren, He, Xu, Guogang, Feng, Xiaoming
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6294005/
https://ncbi.nlm.nih.gov/pubmed/30546010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07545-8
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky