Cbx4 maintains the epithelial lineage identity and cell proliferation in the developing stratified epithelium

During development, multipotent progenitor cells establish lineage-specific programmers of gene activation and silencing underlying their differentiation into specialized cell types. We show that the Polycomb component Cbx4 serves as a critical determinant that maintains the epithelial identity in t...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Mardaryev, Andrei N., Liu, Bo, Rapisarda, Valentina, Poterlowicz, Krzysztof, Malashchuk, Igor, Rudolf, Jana, Sharov, Andrey A., Jahoda, Colin A., Fessing, Michael Y., Benitah, Salvador A., Xu, Guo-Liang, Botchkarev, Vladimir A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2016
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4700479/
https://ncbi.nlm.nih.gov/pubmed/26711500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201506065
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