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Small molecule-mediated inhibition of β-2-microglobulin-based amyloid fibril formation
In dialysis patients, β-2 microglobulin (β2m) can aggregate and eventually form amyloid fibrils in a condition known as dialysis-related amyloidosis, which deleteriously affects joint and bone function. Recently, several small molecules have been identified as potential inhibitors of β2m amyloid for...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5481568/ https://ncbi.nlm.nih.gov/pubmed/28468825 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.774083 |
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