Effect of Tetracyclines on the Dynamics of Formation and Destructuration of β2-Microglobulin Amyloid Fibrils

The discovery of methods suitable for the conversion in vitro of native proteins into amyloid fibrils has shed light on the molecular basis of amyloidosis and has provided fundamental tools for drug discovery. We have studied the capacity of a small library of tetracycline analogues to modulate the...

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Main Authors: Giorgetti, Sofia, Raimondi, Sara, Pagano, Katiuscia, Relini, Annalisa, Bucciantini, Monica, Corazza, Alessandra, Fogolari, Federico, Codutti, Luca, Salmona, Mario, Mangione, Palma, Colombo, Lino, De Luigi, Ada, Porcari, Riccardo, Gliozzi, Alessandra, Stefani, Massimo, Esposito, Gennaro, Bellotti, Vittorio, Stoppini, Monica
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2011
נושאים:
Protein Structure and Folding
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023509/
https://ncbi.nlm.nih.gov/pubmed/21068391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.178376
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