Effect of Tetracyclines on the Dynamics of Formation and Destructuration of β2-Microglobulin Amyloid Fibrils

The discovery of methods suitable for the conversion in vitro of native proteins into amyloid fibrils has shed light on the molecular basis of amyloidosis and has provided fundamental tools for drug discovery. We have studied the capacity of a small library of tetracycline analogues to modulate the...

Full description

Saved in:
Bibliographic Details
Main Authors: Giorgetti, Sofia, Raimondi, Sara, Pagano, Katiuscia, Relini, Annalisa, Bucciantini, Monica, Corazza, Alessandra, Fogolari, Federico, Codutti, Luca, Salmona, Mario, Mangione, Palma, Colombo, Lino, De Luigi, Ada, Porcari, Riccardo, Gliozzi, Alessandra, Stefani, Massimo, Esposito, Gennaro, Bellotti, Vittorio, Stoppini, Monica
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2011
Subjects:
Protein Structure and Folding
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023509/
https://ncbi.nlm.nih.gov/pubmed/21068391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.178376
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items