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A functional mTORC1 signaling is indispensable for c-Myc driven hepatocarcinogenesis

Amplification and/or activation of the c-Myc protooncogene is one of the leading genetic events along hepatocarcinogenesis. The oncogenic potential of c-Myc has been proven experimentally by the finding that its overexpression in the mouse liver triggers tumor formation. However, the molecular mecha...

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מידע ביבליוגרפי
הוצא לאור ב:	Hepatology
Main Authors:	Liu, Pin, Ge, Mengmeng, Hu, Junjie, Li, Xiaolei, Che, Li, Sun, Kun, Cheng, Lili, Huang, Yuedong, Pilo, Maria G., Cigliano, Antonio, Pes, Giovanni M., Pascale, Rosa M., Brozzetti, Stefania, Vidili, Gianpaolo, Porcu, Alberto, Cossu, Antonio, Palmieri, Giuseppe, Sini, Maria C., Ribback, Silvia, Dombrowski, Frank, Tao, Junyan, Calvisi, Diego F., Chen, Ligong, Chen, Xin
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	2017
נושאים:	Article
גישה מקוונת:	https://ncbi.nlm.nih.gov/pmc/articles/PMC5481473/ https://ncbi.nlm.nih.gov/pubmed/28370287 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.29183
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A functional mTORC1 signaling is indispensable for c-Myc driven hepatocarcinogenesis

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